The earth’s climate is changing rapidly and the development, by breeding, of new high-yielding and climate adapted varieties of agricultural crops is currently too low to tackle forthcoming threats to food security. The EU-funded BREEDIT project developed an innovative breeding strategy to quickly assess combinations of potential yield contributing alleles. By multiplex gene editing a large number of genes in combination with breeding, phenotyping and multiplex amplicon sequencing and machine learning, gene combinations can be identified that modify beneficial traits in crops. The technology was developed with maize a model but can be applied for a large number of crops.
This work is supported by the European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation Program (H2020/2019-2025) under grant agreement No 833866-BREEDIT.