Inze Dirk

Inze Dirk - Group leader - Emeritus
Joined the group in 1979

Dirk Inzé is a global leader in plant biology and an ISI ‘most cited author’. His research ambition is to obtain a holistic understanding of the molecular networks regulating plant organ growth and crop productivity. His work has opened up new perspectives for the identification of optimal growth regulatory networks that can be selected by advanced breeding, or for which more robust variants can be obtained through genetic engineering. As such, Dirk Inzé's work significantly contributes to providing food security for the growing world population.
Dirk Inzé received his PhD at Ghent in 1984. In 1990, he was appointed Research Director of the French National Institute for Agricultural Research (INRA), where he initiated highly successful research programs on the plant cell cycle and growth control. In 1995, he became Professor at Ghent University and he was the scientific founder of the biotechnology company CropDesign, which was established in 1998 and acquired in 2006 by BASF Plant Science. In 2002, Dirk was appointed Director of the Center for Plant Systems Biology of the VIB. Under his directorship, the Center for Plant Systems Biology – currently employing approximately 300 individuals – became one of the world leading centers for advanced plant sciences. Dirk’s research was recognized by numerous awards and he is a member of several science advisory boards. Dirk currently owns, for the second time, an advanced ERC grant and his work received >56,000 citations (H-factor 132). In 2017, Dirk was awarded with the prestigious World Agriculture Prize. In 2019 he was elected to the rank of AAAS Fellow by the American Association for the Advancement of Science (AAAS). In 2020 he became an elected member of Academia Europaea.

Wytynck Pieter

Wytynck Pieter - Postdoctoral fellow
Joined the group in 2022

I studied Bioscience Engineering at the university of Ghent focusing on Cell and Gene Biotechnology. After obtaining my masters, I did a PhD on improving the abiotic stress tolerance in crop species. Subsequently, I worked for 2,5 years at Biogazelle which is a Contract Research Organization (CRO) specializing in DNA- and RNA-based applications to support pharmaceutical research, clinical trials and diagnostic test development. As a scientist I provided scientific guidance to ongoing projects and R&D activities. Currently, I work as a postdoctoral researcher on the use of AI/Machine Learning in plant breeding on the BREEDIT project.

Beauchet Arthur

Beauchet Arthur - Postdoctoral fellow
Joined the group in 2022

I am a Post-doctoral researcher in plant cell and molecular biology in the field of organ growth, crop productivity. After I obtained my master degree of plant biology and biotechnology at Bordeaux university, I graduated with my PhD in 2022 where I studied the molecular mechanisms controlling Tomato fruit organogenesis and fruit size determination in the Flowering, Fruit Development and Environmental Constraints team at INRAe. My PhD consisted in studying the functional role of FW2.2, the protein associated to the major QTL governing fruit weight in tomato. I demonstrated that FW2.2 is associated with Plasmodesmata and is involved in cell-to-cell communication by modifying the callose deposition status, so that the aperture of Plasmodesmata is modified. Since October 2022, I joined the systems biology of yield and the innovative breeding groups to work on the EU-funded BREEDIT project which aims at developing a flexible pipeline that combines multiplex gene editing of genes related to growth and yield-traits and different crossing schemes to generate plants with modified traits. Taking advantages of BREEDIT, I am currently using multiplex genome editing to target Cis-regulatory regions of known negative growth regulators. My academic training and research experiences have provided me an excellent background in multiple domains including plant cell biology, molecular biology, genetic engineering and plant development. I had to adapt to different working environments and study different plant models (Tomato, Tobacco, Arabidopsis thaliana, Brachypodium distachyon and Maize) to carry out my work. I have gained expertise with a lot of different techniques such as molecular cloning (Gateway and Goldengate) and tomato transgenesis, multiplex genome editing using CRISPR/Cas9, Cis-regulatory regions targeting with CRISPR/Cas9, GUS staining, phenotyping, in situ hybridization and microscopy.

Lorenzo Christian

Lorenzo Christian - Postdoctoral fellow
Joined the group in 2019

PSB - Systems biology of Yield

I am a senior Argentinian postdoctoral researcher in the lab of Profs. Dirk Inzé and Hilde Nelissen at the VIB Ugent Center for Plant Systems Biology (PSB) in Belgium. My primary research interest lies in the study of how gene networks shape plant physiological responses and how this information can be translated into trait improvements in maize. I earned a PhD in biological sciences from the University of Buenos Aires (UBA) and did my thesis under the supervision of Prof. Pablo Cerdán in Fundación Instituto Leloir (Buenos Aires). During my PhD i studied the conservation of flowering mechanisms between Arabidopsis thaliana and the forage crop Medicago sativa (alfalfa) in order to improve its biomass quality. I later did a first postdoc in Prof. Marcelo Yanovsky’s lab where i studied the shade avoidance responses of soybean and alfalfa, aiming to create improved yielding varieties suited for high-density cultivation. Presently i work in BREEDIT, a multidisciplinary ERC funded project combining both gene editing and classical breeding aspects in maize with the objective of improving yield and drought resistance in this crop.

21 VIB researchers recognized as Clarivate Highly Cited Researchers 2024

Each year, Clarivate honors the world's ‘Highly Cited Researchers’ – exceptional scientists whose work ranks among the top 1% most cited in their field, showcasing their groundbreaking influence on global research. This year, we're excited to announce that 21 VIB researchers have earned this prestigious recognition for their remarkable contributions to science.

Dirk Inzé and Peter Carmeliet elected as members of the European Academy of Engineering.

Dirk Inzé, Professor Emeritus at the University of Ghent and former head of the VIB-UGent Center for Plant Systems Biology has been elected as a Member of Class of Fundamental Sciences and Mathematics Science (F.M.S.) at the European Academy of Engineering (EAE) in Sweden. Simultaneously, Peter Carmeliet, Professor at the VIB-KU Leuven Center for Cancer Biology has been elected as a Member of the Class of Biomedical Engineering (B.M.E). The President of the EAE communicated this prestigious honor on May 27th in a congratulatory letter to both Dirk and Peter.

New variations on an old theme

During breeding segregating populations are created, which prohibit rigorous statistical analyses. To circumvent this issue, we have developed a double haploid (DH) pipeline (in collaboration with PSB’s crop genome facility) which has the power to greatly assisted in the identification of causative gene combinations. The haploid inducer BREEDIT strategy (HI-BREEDIT) allows the generation of fixed multiple gene edited lines of different orders which can be propagated indeterminately and provide a powerful resource for genetical and molecular analyses.